Here we take you through a step by step process of helping you to assess, understand and reduce your risk of breast and ovarian cancer.
A: Cancer is a common disease so most families will have some members who have had cancer. Hereditary cancer occurs when a person is born with mutations in certain genes which normally protect against cancer. These mutations can be passed down from one generation to the next and, importantly, can come from either side of the family. You may have heard of BRCA1 or BRCA2. These are the most common genes known to be associated with hereditary breast and ovarian cancer. Other gene mutations have been identified but are not as well studied and others are yet to be identified. It is important to remember that not everyone born with a gene mutation will develop cancer.
A: Women with a BRCA gene mutation have a risk of between 40% and 80% for breast cancer and 10% and 40% for ovarian cancer over their lifetime.
A: Australian statistics determine that about 5% of breast and up to 15% of ovarian cancers are due to an inherited faulty gene.
A: There are three simple questions that can help you determine whether there is a risk of hereditary cancer in your family: 1. Have any of your blood relatives had cancer? 2. What types of cancer were they? 3. How old were they when they developed cancer? For further details on what to collect, a mapping template and tips for talking to your family see Pink Hope’s Kiss and Tell resources.
A: After researching and documenting your family health history you may find it helpful to complete the Pink Hope Assess Your Risk tool. You can then discuss these results with your GP. If you and your GP have concerns about your level of cancer risk your GP can refer you to see a Genetic Counsellor at a Family Cancer Clinic which is covered by Medicare and Family Cancer Clinics are located throughout Australia. You can also submit questions to the Pink Hope Online Genetic Counsellor to help you identify and manage your risk.
A: Women who know they carry a BRCA gene mutation can take proactive steps such as self checks, getting screened regularly which can include mammograms, ultrasounds and MRIs. Risk reducing medication and preventative surgery are also two other options to reduce breast and ovarian cancer risk. The Pink Hope website has further information on ways to reduce your risk and risk reducing measures.
A: Yes. Both women and men can carry the defective gene. They also have a 50/50 chance of passing it on to their child.
A: If a genetic fault has already been found in your family:
A: Many men do not realise that they can inherit BRCA mutations and can then pass them on to their children. They may also not realise that having a BRCA mutation may mean that they need to be more aware of breast changes, and to seek regular prostate screening blood tests from the family doctor. The publication Understanding genetic tests for men with a family history of breast and ovarian cancer is available through the Centre for Genetics Education.
Know Your Risk Tool
Risk Factors
Your Body and Your Doctor
Genetic Risk
Genetic Testing 101
Understand Your Risk
Risk Reducing Actions
Lifestyle Factors